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A multi-use vial at low doses will last longer than at higher doses, potentially several weeks

In a small CSF substudy (~199 participants), modest reductions of ~810% were observed with semaglutide versus placebo in several Alzheimers diseaserelated markers, including pTau181, pTau217, total tau, neurogranin, and YKL40

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It takes 5-6 half-lives for the drug to clear from the system

Maintenance dosing with 60 mg vials Once you have titrated to your target dose, the 60 mg vial becomes straightforward: At a 10 mg maintenance dose, you need roughly 9 vials per year